CANAlization: Control & Redundancy in Boolean Networks


This package implements a series of methods used to study control, canalization and redundancy in Boolean Networks.

If you are using this package, please consider citing the following papers, including our latest describing CANA.

[CGWR18] “R.B. Correia, A. Gates, X. Wang and L.M. Rocha [2018]. “CANA: A python package for quantifying control and canalization in Boolean Networks.” Frontiers in Physiology, 9: 1046. doi: 10.3389/fphys.2018.01046.”

The original mathematical descriptions implemented in CANA can be seen in these papers.

[GR16] “A. Gates and L.M. Rocha. [2016] “Control of complex networks requires both structure and dynamics.” Scientific Reports 6, 24456. doi: 10.1038/srep24456.”

[GR14] “A. Gates and L.M. Rocha [2014]. “Structure and dynamics affect the controllability of complex systems: a Preliminary Study”. Artificial Life 14: Proceedings of the Fourteenth International Conference on the Synthesis and Simulation of Living Systems: 429-430, MIT Press.”

[MPR13] “M. Marques-Pita and L.M. Rocha [2013]. “Canalization and control in automata networks: body segmentation in Drosophila Melanogaster”. PLoS ONE, 8 (3): e55946. doi:10.1371/journal.pone.0055946.”

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